The Stem Cell Project

Cline is collaborating with a team at Sahlgrenska that is developing an allogenic stem cell therapy based on induced pluripotent stem (iPS) cells that can self-heal cartilage.

Organs and tissue such as cartilage and limbs are formed during embryonic development due to an orchestration of growth factors that functions as morphogens which can specify more than one cell type due to forming a concentration gradient in humans and vertebrates. 

In StemCART, morphogens are functionalized on gold nanoparticle gradient surfaces and are used during differentiation of iPS cells into the chondrogenic lineage to provide a unique, defined and growth promoting environment with molecular precision.

To read more about our StemCART project, please click here.